• Unlimited

  • Lightweight

  • Equivalent

Innovative point-of-care, tankless electric Nitric Oxide for hospital, ambulatory and home use.

The Third Pole™ core technology is an innovative clean, tankless inhaled Nitric Oxide (NO) proven equivalent to marketed tank-gas in the lab.  Nitric oxide saves hypoxic newborns, but is available only in a limited number of countries, for those who can afford it, by physicians who have access to the product. We intend to make NO available worldwide.  Click to read about our technology featured on the cover of SCIENCE Translational Medicine, July 1, 2015.

 

BREAKING NEWS (5/4/17)
Third Pole, Inc., Wins Johnson & Johnson Innovation’s JLABS @ M2D2 QuickFire Challenge
Read full release: Word | PDF

The NO Story

Electric NO Advantages

Point-of-care (POC) NO is designed to address current concerns with delivery systems for NO around safety, reliability, usability, logistics and access. Our solution is:

  • Lightweight
  • Chemically equivalent
  • Generates an unlimited supply of NO gas

We are developing products that will revolutionize the delivery of NO.

Who needs NO?

Approximately 10,000 “blue babies” breathe NO to treat Hypoxic Respiratory Failure in the Newborn annually. The average cost of nitric oxide is $14,000+ per neonate.

Other uses for Nitric Oxide have been explored including Malaria, heart attacks and strokes. We believe that this is an expanding market, that will only be improved with additional options in the marketplace.




"Cost of nitric oxide is exorbitant."

British Medical Journal



Meet the Team

David Zapol
David Zapol

Founder and CEO David Zapol leads start-up operations. He is co-founder and previously led operations of Africa Chemist and Beauty Care, the largest pharmacy chain in East Africa. David was a lead of the Global Health strategy consulting practice at FSG. David holds an MBA/MPH from Columbia and a Masters in Immunology from Stanford.

Philip E. Silkoff
Philip E. Silkoff

Chief Medical Officer Philip E. Silkoff is an experienced senior pharmaceutical physician previously at AstraZeneca and Janssen R&D. Phil has overseen multiple clinical studies in asthma, COPD, interstitial pulmonary fibrosis and sarcoidosis. Prior to industry, Phil was Associate Professor at National Jewish Health in Denver, Colorado. Phil is a renowned expert in exhaled nitric oxide measurement and holds several patents in the field.

Greg Hall
Greg Hall

Vice President, Product Development Greg Hall, Ph.D is technical leader and engineer with 18 years experience in the medical device industry. Prior to joining Third Pole, Greg served as General Manager at Cirtec Medical and has been VP of Engineering for several medical device development endeavors. Greg has led development programs for software-controlled electromechanical systems through clinical evaluation and regulatory approval and is an inventor on more than 12 issued patents. His formal education includes a Ph.D. from the University of Virginia, a Masters degree from Clemson University in Bioengineering and a BS degree in mechanical engineering from Rose-Hulman Institute of Technology.

Ashleigh Palmer
Ashleigh Palmer

Board Member Ashleigh Palmer was Founder, CEO and President of iNOTherapeutics, which brought inhaled NO to market and was bought by Ikaria for $670M. Ashleigh is a start-up and biotech leader advising on partnering, marketing and strategy of Third Pole.

Warren Zapol
Warren Zapol

Scientific Advisory Board Chairman Warren Zapol was a co-inventor on our key patents from MGH, and is a co-inventor of inhaled Nitric Oxide, for which he received the 2003 Inventor of the Year award from the Intellectual Property Owners Association.

Jeffrey Scott McCormick
Jeffrey Scott McCormick

Board Member Jeffrey Scott McCormick is Managing Partner with Saturn Partners which he founded in 1994 to finance early-stage growth companies. Working closely with Third Pole™ he is helping to forge strategic relationships, build the management team, and develop marketing and distribution strategies to enable significant growth.


Work with Us

Come join our dynamic cross-functional team to design, build and roll-out our new world changing products.

 

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